医薬品及び賦形剤のグローバル市場展望 2023年-2029年:中性脂肪、マンニトール、ソルビトール、ショ糖、ブドウ糖、でんぷん、その他

■ 英語タイトル:Pharmaceuticals and Excipients Market, Global Outlook and Forecast 2023-2029

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■ 発行日:2023年7月
■ 調査対象地域:グローバル、北米、アメリカ、ヨーロッパ、アジア、日本、中国、東南アジア、インド、南米、中東・アフリカなど
■ 産業分野:医薬品&ヘルスケア
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★グローバルリサーチ資料[医薬品及び賦形剤のグローバル市場展望 2023年-2029年:中性脂肪、マンニトール、ソルビトール、ショ糖、ブドウ糖、でんぷん、その他]についてメールでお問い合わせはこちら
*** レポート概要(サマリー)***

当調査レポートは次の情報を含め、世界の医薬品及び賦形剤市場規模と予測を収録しています。・世界の医薬品及び賦形剤市場:売上、2018年-2023年、2024年-2029年
・世界の医薬品及び賦形剤市場:販売量、2018年-2023年、2024年-2029年
・世界のトップ5企業、2022年

世界の医薬品及び賦形剤市場は2022年に000Mドルと評価され、予測期間中に000%のCAGRで2029年までに000Mドルに達すると予測されています。米国市場は2022年に000Mドルと推定されており、中国は2029年までに000Mドルに達すると予測されています。「中性脂肪」セグメントは今後6年間、000%のCAGRで2029年までに000Mドルに成長すると予測されています。

医薬品及び賦形剤のグローバル主要企業は、Dow、 BASF、 ER-KANG、 JRS Pharma、 Lubrizol、 Ashland、 Roquette、 Shin-Etsu、 Evonik、 ABITEC Corp、 Signet Chemical Corporation、 Sigachi Industries、 MEGGLE AGなどです。2022年にトップ5企業がグローバル売上シェアの約000%を占めています。

MARKET MONITOR GLOBAL(MMG)は、医薬品及び賦形剤のメーカー、サプライヤー、流通業者、および業界の専門家を調査しました。これには、販売量、売上、需要、価格変動、製品タイプ、最近の動向と計画、産業トレンド、成長要因、課題、阻害要因、潜在的なリスクなどが含まれます。

【セグメント別市場分析】

世界の医薬品及び賦形剤市場:タイプ別、2018年-2023年、2024年-2029年
世界の医薬品及び賦形剤市場:タイプ別市場シェア、2022年
・中性脂肪、マンニトール、ソルビトール、ショ糖、ブドウ糖、でんぷん、その他

世界の医薬品及び賦形剤市場:用途別、2018年-2023年、2024年-2029年
世界の医薬品及び賦形剤市場:用途別市場シェア、2022年
・経口剤、外用剤、非経口剤、その他

世界の医薬品及び賦形剤市場:地域・国別、2018年-2023年、2024年-2029年
世界の医薬品及び賦形剤市場:地域別市場シェア、2022年
・北米:アメリカ、カナダ、メキシコ
・ヨーロッパ:ドイツ、フランス、イギリス、イタリア、ロシア
・アジア:中国、日本、韓国、東南アジア、インド
・南米:ブラジル、アルゼンチン
・中東・アフリカ:トルコ、イスラエル、サウジアラビア、UAE

【競合分析】

また、当レポートは主要な市場参加者の分析を提供します。
・主要企業における医薬品及び賦形剤のグローバル売上、2018年-2023年
・主要企業における医薬品及び賦形剤のグローバル売上シェア、2022年
・主要企業における医薬品及び賦形剤のグローバル販売量、2018年-2023年
・主要企業における医薬品及び賦形剤のグローバル販売量シェア、2022年

さらに、当レポートは主要企業のプロファイルを提示します。
Dow、 BASF、 ER-KANG、 JRS Pharma、 Lubrizol、 Ashland、 Roquette、 Shin-Etsu、 Evonik、 ABITEC Corp、 Signet Chemical Corporation、 Sigachi Industries、 MEGGLE AG

*************************************************************

・調査・分析レポートの概要
医薬品及び賦形剤市場の定義
市場セグメント
世界の医薬品及び賦形剤市場概要
当レポートの特徴・ベネフィット
調査手法と情報源

・世界の医薬品及び賦形剤市場規模
世界の医薬品及び賦形剤市場規模:2022年 VS 2029年
世界の医薬品及び賦形剤市場規模と予測 2018年-2029年

・競争状況
グローバルトップ企業
売上ベースでのグローバルトップ企業
企業別グローバルでの医薬品及び賦形剤の売上
グローバルトップ3およびトップ5企業、2022年売上ベース
グローバル企業の医薬品及び賦形剤製品タイプ
グローバルにおけるティア1、ティア2、ティア3企業

・タイプ別市場分析
タイプ区分:中性脂肪、マンニトール、ソルビトール、ショ糖、ブドウ糖、でんぷん、その他
医薬品及び賦形剤のタイプ別グローバル売上・予測

・用途別市場分析
用途区分:経口剤、外用剤、非経口剤、その他
医薬品及び賦形剤の用途別グローバル売上・予測

・地域別市場分析
地域別医薬品及び賦形剤市場規模 2022年と2029年
地域別医薬品及び賦形剤売上・予測
北米市場:アメリカ、カナダ、メキシコ
ヨーロッパ市場:ドイツ、フランス、イギリス、イタリア、ロシア
アジア市場:中国、日本、韓国、東南アジア、インド
南米市場:ブラジル、アルゼンチン
中東・アフリカ市場:トルコ、イスラエル、サウジアラビア、UAE

・主要企業のプロファイル(企業概要、事業概要、主要製品、売上、ニュースなど)
Dow、 BASF、 ER-KANG、 JRS Pharma、 Lubrizol、 Ashland、 Roquette、 Shin-Etsu、 Evonik、 ABITEC Corp、 Signet Chemical Corporation、 Sigachi Industries、 MEGGLE AG
...

Pharmaceutical Excipients are any materials that are added to the drug formulation other than API (Active Pharmaceutical Ingredient) in order to fill up the dosage form (fillers) OR to aid in formulation (Binders, disintegrants, glidents, lubricants) OR to aid in stabilizing the drug product (Preservatives) OR to aid palatability (Sweeteners, flavors, colorants) OR to aid modified release (Polymers, coating materials) etc.,
This report aims to provide a comprehensive presentation of the global market for Pharmaceuticals and Excipients, with both quantitative and qualitative analysis, to help readers develop business/growth strategies, assess the market competitive situation, analyze their position in the current marketplace, and make informed business decisions regarding Pharmaceuticals and Excipients. This report contains market size and forecasts of Pharmaceuticals and Excipients in global, including the following market information:
Global Pharmaceuticals and Excipients Market Revenue, 2018-2023, 2024-2029, ($ millions)
Global Pharmaceuticals and Excipients Market Sales, 2018-2023, 2024-2029, (Kiloton)
Global top five Pharmaceuticals and Excipients companies in 2022 (%)
The global Pharmaceuticals and Excipients market was valued at US$ million in 2022 and is projected to reach US$ million by 2029, at a CAGR of % during the forecast period. The influence of COVID-19 and the Russia-Ukraine War were considered while estimating market sizes.
The U.S. Market is Estimated at $ Million in 2022, While China is Forecast to Reach $ Million.
Triglycerides Segment to Reach $ Million by 2029, with a % CAGR in next six years.
The global key manufacturers of Pharmaceuticals and Excipients include Dow, BASF, ER-KANG, JRS Pharma, Lubrizol, Ashland, Roquette, Shin-Etsu and Evonik, etc. in 2022, the global top five players have a share approximately % in terms of revenue.
MARKET MONITOR GLOBAL, INC (MMG) has surveyed the Pharmaceuticals and Excipients manufacturers, suppliers, distributors and industry experts on this industry, involving the sales, revenue, demand, price change, product type, recent development and plan, industry trends, drivers, challenges, obstacles, and potential risks.
Total Market by Segment:
Global Pharmaceuticals and Excipients Market, by Type, 2018-2023, 2024-2029 ($ Millions) & (Kiloton)
Global Pharmaceuticals and Excipients Market Segment Percentages, by Type, 2022 (%)
Triglycerides
Mannitol
Sorbitol
Sucrose
Dextrose
Starch
Others
Global Pharmaceuticals and Excipients Market, by Application, 2018-2023, 2024-2029 ($ Millions) & (Kiloton)
Global Pharmaceuticals and Excipients Market Segment Percentages, by Application, 2022 (%)
Oral Formulations
Topical Formulations
Parenteral Formulations
Other
Global Pharmaceuticals and Excipients Market, By Region and Country, 2018-2023, 2024-2029 ($ Millions) & (Kiloton)
Global Pharmaceuticals and Excipients Market Segment Percentages, By Region and Country, 2022 (%)
North America
US
Canada
Mexico
Europe
Germany
France
U.K.
Italy
Russia
Nordic Countries
Benelux
Rest of Europe
Asia
China
Japan
South Korea
Southeast Asia
India
Rest of Asia
South America
Brazil
Argentina
Rest of South America
Middle East & Africa
Turkey
Israel
Saudi Arabia
UAE
Rest of Middle East & Africa
Competitor Analysis
The report also provides analysis of leading market participants including:
Key companies Pharmaceuticals and Excipients revenues in global market, 2018-2023 (Estimated), ($ millions)
Key companies Pharmaceuticals and Excipients revenues share in global market, 2022 (%)
Key companies Pharmaceuticals and Excipients sales in global market, 2018-2023 (Estimated), (Kiloton)
Key companies Pharmaceuticals and Excipients sales share in global market, 2022 (%)
Further, the report presents profiles of competitors in the market, key players include:
Dow
BASF
ER-KANG
JRS Pharma
Lubrizol
Ashland
Roquette
Shin-Etsu
Evonik
ABITEC Corp
Signet Chemical Corporation
Sigachi Industries
MEGGLE AG
Outline of Major Chapters:
Chapter 1: Introduces the definition of Pharmaceuticals and Excipients, market overview.
Chapter 2: Global Pharmaceuticals and Excipients market size in revenue and volume.
Chapter 3: Detailed analysis of Pharmaceuticals and Excipients manufacturers competitive landscape, price, sales and revenue market share, latest development plan, merger, and acquisition information, etc.
Chapter 4: Provides the analysis of various market segments by type, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different market segments.
Chapter 5: Provides the analysis of various market segments by application, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different downstream markets.
Chapter 6: Sales of Pharmaceuticals and Excipients in regional level and country level. It provides a quantitative analysis of the market size and development potential of each region and its main countries and introduces the market development, future development prospects, market space of each country in the world.
Chapter 7: Provides profiles of key players, introducing the basic situation of the main companies in the market in detail, including product sales, revenue, price, gross margin, product introduction, recent development, etc.
Chapter 8: Global Pharmaceuticals and Excipients capacity by region & country.
Chapter 9: Introduces the market dynamics, latest developments of the market, the driving factors and restrictive factors of the market, the challenges and risks faced by manufacturers in the industry, and the analysis of relevant policies in the industry.
Chapter 10: Analysis of industrial chain, including the upstream and downstream of the industry.
Chapter 11: The main points and conclusions of the report.

*** レポート目次(コンテンツ)***

1 Introduction to Research & Analysis Reports
1.1 Pharmaceuticals and Excipients Market Definition
1.2 Market Segments
1.2.1 Market by Type
1.2.2 Market by Application
1.3 Global Pharmaceuticals and Excipients Market Overview
1.4 Features & Benefits of This Report
1.5 Methodology & Sources of Information
1.5.1 Research Methodology
1.5.2 Research Process
1.5.3 Base Year
1.5.4 Report Assumptions & Caveats
2 Global Pharmaceuticals and Excipients Overall Market Size
2.1 Global Pharmaceuticals and Excipients Market Size: 2022 VS 2029
2.2 Global Pharmaceuticals and Excipients Revenue, Prospects & Forecasts: 2018-2029
2.3 Global Pharmaceuticals and Excipients Sales: 2018-2029
3 Company Landscape
3.1 Top Pharmaceuticals and Excipients Players in Global Market
3.2 Top Global Pharmaceuticals and Excipients Companies Ranked by Revenue
3.3 Global Pharmaceuticals and Excipients Revenue by Companies
3.4 Global Pharmaceuticals and Excipients Sales by Companies
3.5 Global Pharmaceuticals and Excipients Price by Manufacturer (2018-2023)
3.6 Top 3 and Top 5 Pharmaceuticals and Excipients Companies in Global Market, by Revenue in 2022
3.7 Global Manufacturers Pharmaceuticals and Excipients Product Type
3.8 Tier 1, Tier 2 and Tier 3 Pharmaceuticals and Excipients Players in Global Market
3.8.1 List of Global Tier 1 Pharmaceuticals and Excipients Companies
3.8.2 List of Global Tier 2 and Tier 3 Pharmaceuticals and Excipients Companies
4 Sights by Product
4.1 Overview
4.1.1 By Type – Global Pharmaceuticals and Excipients Market Size Markets, 2022 & 2029
4.1.2 Triglycerides
4.1.3 Mannitol
4.1.4 Sorbitol
4.1.5 Sucrose
4.1.6 Dextrose
4.1.7 Starch
4.1.8 Others
4.2 By Type – Global Pharmaceuticals and Excipients Revenue & Forecasts
4.2.1 By Type – Global Pharmaceuticals and Excipients Revenue, 2018-2023
4.2.2 By Type – Global Pharmaceuticals and Excipients Revenue, 2024-2029
4.2.3 By Type – Global Pharmaceuticals and Excipients Revenue Market Share, 2018-2029
4.3 By Type – Global Pharmaceuticals and Excipients Sales & Forecasts
4.3.1 By Type – Global Pharmaceuticals and Excipients Sales, 2018-2023
4.3.2 By Type – Global Pharmaceuticals and Excipients Sales, 2024-2029
4.3.3 By Type – Global Pharmaceuticals and Excipients Sales Market Share, 2018-2029
4.4 By Type – Global Pharmaceuticals and Excipients Price (Manufacturers Selling Prices), 2018-2029
5 Sights by Application
5.1 Overview
5.1.1 By Application – Global Pharmaceuticals and Excipients Market Size, 2022 & 2029
5.1.2 Oral Formulations
5.1.3 Topical Formulations
5.1.4 Parenteral Formulations
5.1.5 Other
5.2 By Application – Global Pharmaceuticals and Excipients Revenue & Forecasts
5.2.1 By Application – Global Pharmaceuticals and Excipients Revenue, 2018-2023
5.2.2 By Application – Global Pharmaceuticals and Excipients Revenue, 2024-2029
5.2.3 By Application – Global Pharmaceuticals and Excipients Revenue Market Share, 2018-2029
5.3 By Application – Global Pharmaceuticals and Excipients Sales & Forecasts
5.3.1 By Application – Global Pharmaceuticals and Excipients Sales, 2018-2023
5.3.2 By Application – Global Pharmaceuticals and Excipients Sales, 2024-2029
5.3.3 By Application – Global Pharmaceuticals and Excipients Sales Market Share, 2018-2029
5.4 By Application – Global Pharmaceuticals and Excipients Price (Manufacturers Selling Prices), 2018-2029
6 Sights by Region
6.1 By Region – Global Pharmaceuticals and Excipients Market Size, 2022 & 2029
6.2 By Region – Global Pharmaceuticals and Excipients Revenue & Forecasts
6.2.1 By Region – Global Pharmaceuticals and Excipients Revenue, 2018-2023
6.2.2 By Region – Global Pharmaceuticals and Excipients Revenue, 2024-2029
6.2.3 By Region – Global Pharmaceuticals and Excipients Revenue Market Share, 2018-2029
6.3 By Region – Global Pharmaceuticals and Excipients Sales & Forecasts
6.3.1 By Region – Global Pharmaceuticals and Excipients Sales, 2018-2023
6.3.2 By Region – Global Pharmaceuticals and Excipients Sales, 2024-2029
6.3.3 By Region – Global Pharmaceuticals and Excipients Sales Market Share, 2018-2029
6.4 North America
6.4.1 By Country – North America Pharmaceuticals and Excipients Revenue, 2018-2029
6.4.2 By Country – North America Pharmaceuticals and Excipients Sales, 2018-2029
6.4.3 US Pharmaceuticals and Excipients Market Size, 2018-2029
6.4.4 Canada Pharmaceuticals and Excipients Market Size, 2018-2029
6.4.5 Mexico Pharmaceuticals and Excipients Market Size, 2018-2029
6.5 Europe
6.5.1 By Country – Europe Pharmaceuticals and Excipients Revenue, 2018-2029
6.5.2 By Country – Europe Pharmaceuticals and Excipients Sales, 2018-2029
6.5.3 Germany Pharmaceuticals and Excipients Market Size, 2018-2029
6.5.4 France Pharmaceuticals and Excipients Market Size, 2018-2029
6.5.5 U.K. Pharmaceuticals and Excipients Market Size, 2018-2029
6.5.6 Italy Pharmaceuticals and Excipients Market Size, 2018-2029
6.5.7 Russia Pharmaceuticals and Excipients Market Size, 2018-2029
6.5.8 Nordic Countries Pharmaceuticals and Excipients Market Size, 2018-2029
6.5.9 Benelux Pharmaceuticals and Excipients Market Size, 2018-2029
6.6 Asia
6.6.1 By Region – Asia Pharmaceuticals and Excipients Revenue, 2018-2029
6.6.2 By Region – Asia Pharmaceuticals and Excipients Sales, 2018-2029
6.6.3 China Pharmaceuticals and Excipients Market Size, 2018-2029
6.6.4 Japan Pharmaceuticals and Excipients Market Size, 2018-2029
6.6.5 South Korea Pharmaceuticals and Excipients Market Size, 2018-2029
6.6.6 Southeast Asia Pharmaceuticals and Excipients Market Size, 2018-2029
6.6.7 India Pharmaceuticals and Excipients Market Size, 2018-2029
6.7 South America
6.7.1 By Country – South America Pharmaceuticals and Excipients Revenue, 2018-2029
6.7.2 By Country – South America Pharmaceuticals and Excipients Sales, 2018-2029
6.7.3 Brazil Pharmaceuticals and Excipients Market Size, 2018-2029
6.7.4 Argentina Pharmaceuticals and Excipients Market Size, 2018-2029
6.8 Middle East & Africa
6.8.1 By Country – Middle East & Africa Pharmaceuticals and Excipients Revenue, 2018-2029
6.8.2 By Country – Middle East & Africa Pharmaceuticals and Excipients Sales, 2018-2029
6.8.3 Turkey Pharmaceuticals and Excipients Market Size, 2018-2029
6.8.4 Israel Pharmaceuticals and Excipients Market Size, 2018-2029
6.8.5 Saudi Arabia Pharmaceuticals and Excipients Market Size, 2018-2029
6.8.6 UAE Pharmaceuticals and Excipients Market Size, 2018-2029
7 Manufacturers & Brands Profiles
7.1 Dow
7.1.1 Dow Company Summary
7.1.2 Dow Business Overview
7.1.3 Dow Pharmaceuticals and Excipients Major Product Offerings
7.1.4 Dow Pharmaceuticals and Excipients Sales and Revenue in Global (2018-2023)
7.1.5 Dow Key News & Latest Developments
7.2 BASF
7.2.1 BASF Company Summary
7.2.2 BASF Business Overview
7.2.3 BASF Pharmaceuticals and Excipients Major Product Offerings
7.2.4 BASF Pharmaceuticals and Excipients Sales and Revenue in Global (2018-2023)
7.2.5 BASF Key News & Latest Developments
7.3 ER-KANG
7.3.1 ER-KANG Company Summary
7.3.2 ER-KANG Business Overview
7.3.3 ER-KANG Pharmaceuticals and Excipients Major Product Offerings
7.3.4 ER-KANG Pharmaceuticals and Excipients Sales and Revenue in Global (2018-2023)
7.3.5 ER-KANG Key News & Latest Developments
7.4 JRS Pharma
7.4.1 JRS Pharma Company Summary
7.4.2 JRS Pharma Business Overview
7.4.3 JRS Pharma Pharmaceuticals and Excipients Major Product Offerings
7.4.4 JRS Pharma Pharmaceuticals and Excipients Sales and Revenue in Global (2018-2023)
7.4.5 JRS Pharma Key News & Latest Developments
7.5 Lubrizol
7.5.1 Lubrizol Company Summary
7.5.2 Lubrizol Business Overview
7.5.3 Lubrizol Pharmaceuticals and Excipients Major Product Offerings
7.5.4 Lubrizol Pharmaceuticals and Excipients Sales and Revenue in Global (2018-2023)
7.5.5 Lubrizol Key News & Latest Developments
7.6 Ashland
7.6.1 Ashland Company Summary
7.6.2 Ashland Business Overview
7.6.3 Ashland Pharmaceuticals and Excipients Major Product Offerings
7.6.4 Ashland Pharmaceuticals and Excipients Sales and Revenue in Global (2018-2023)
7.6.5 Ashland Key News & Latest Developments
7.7 Roquette
7.7.1 Roquette Company Summary
7.7.2 Roquette Business Overview
7.7.3 Roquette Pharmaceuticals and Excipients Major Product Offerings
7.7.4 Roquette Pharmaceuticals and Excipients Sales and Revenue in Global (2018-2023)
7.7.5 Roquette Key News & Latest Developments
7.8 Shin-Etsu
7.8.1 Shin-Etsu Company Summary
7.8.2 Shin-Etsu Business Overview
7.8.3 Shin-Etsu Pharmaceuticals and Excipients Major Product Offerings
7.8.4 Shin-Etsu Pharmaceuticals and Excipients Sales and Revenue in Global (2018-2023)
7.8.5 Shin-Etsu Key News & Latest Developments
7.9 Evonik
7.9.1 Evonik Company Summary
7.9.2 Evonik Business Overview
7.9.3 Evonik Pharmaceuticals and Excipients Major Product Offerings
7.9.4 Evonik Pharmaceuticals and Excipients Sales and Revenue in Global (2018-2023)
7.9.5 Evonik Key News & Latest Developments
7.10 ABITEC Corp
7.10.1 ABITEC Corp Company Summary
7.10.2 ABITEC Corp Business Overview
7.10.3 ABITEC Corp Pharmaceuticals and Excipients Major Product Offerings
7.10.4 ABITEC Corp Pharmaceuticals and Excipients Sales and Revenue in Global (2018-2023)
7.10.5 ABITEC Corp Key News & Latest Developments
7.11 Signet Chemical Corporation
7.11.1 Signet Chemical Corporation Company Summary
7.11.2 Signet Chemical Corporation Pharmaceuticals and Excipients Business Overview
7.11.3 Signet Chemical Corporation Pharmaceuticals and Excipients Major Product Offerings
7.11.4 Signet Chemical Corporation Pharmaceuticals and Excipients Sales and Revenue in Global (2018-2023)
7.11.5 Signet Chemical Corporation Key News & Latest Developments
7.12 Sigachi Industries
7.12.1 Sigachi Industries Company Summary
7.12.2 Sigachi Industries Pharmaceuticals and Excipients Business Overview
7.12.3 Sigachi Industries Pharmaceuticals and Excipients Major Product Offerings
7.12.4 Sigachi Industries Pharmaceuticals and Excipients Sales and Revenue in Global (2018-2023)
7.12.5 Sigachi Industries Key News & Latest Developments
7.13 MEGGLE AG
7.13.1 MEGGLE AG Company Summary
7.13.2 MEGGLE AG Pharmaceuticals and Excipients Business Overview
7.13.3 MEGGLE AG Pharmaceuticals and Excipients Major Product Offerings
7.13.4 MEGGLE AG Pharmaceuticals and Excipients Sales and Revenue in Global (2018-2023)
7.13.5 MEGGLE AG Key News & Latest Developments
8 Global Pharmaceuticals and Excipients Production Capacity, Analysis
8.1 Global Pharmaceuticals and Excipients Production Capacity, 2018-2029
8.2 Pharmaceuticals and Excipients Production Capacity of Key Manufacturers in Global Market
8.3 Global Pharmaceuticals and Excipients Production by Region
9 Key Market Trends, Opportunity, Drivers and Restraints
9.1 Market Opportunities & Trends
9.2 Market Drivers
9.3 Market Restraints
10 Pharmaceuticals and Excipients Supply Chain Analysis
10.1 Pharmaceuticals and Excipients Industry Value Chain
10.2 Pharmaceuticals and Excipients Upstream Market
10.3 Pharmaceuticals and Excipients Downstream and Clients
10.4 Marketing Channels Analysis
10.4.1 Marketing Channels
10.4.2 Pharmaceuticals and Excipients Distributors and Sales Agents in Global
11 Conclusion
12 Appendix
12.1 Note
12.2 Examples of Clients
12.3 Disclaimer



*** 免責事項 ***
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